Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CASP1 | P29466 | 3/20 | 0.45 |
| ▸ | CASP7 | P55210 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18261131 | 0.82 | HSPA1A (0.57) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16999833 | 0.82 | HSPA1A (0.57) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19976897 | 0.81 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19976901 | 0.80 | GAA (0.59) | MEN1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL19977089 | 0.79 | L3MBTL1 (0.52) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL12308333 | 0.76 | ALDH1A1 (0.62) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19977040 | 0.76 | MAPT (0.71) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL19976914 | 0.76 | PARP1 (0.54) | MEN1KMT2AMAPK1NPC1RAB9A | |
| SCHEMBL19976988 | 0.75 | MEN1 (0.52) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL19977042 | 0.75 | KMT2A (0.52) | MEN1KMT2AL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |