Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | DHPS | P49366 | 8/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.41 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.41 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31156453 | 0.84 | PARP1 (0.72) | PARP1MEN1KMT2ADHPSMAPK1 | |
| SCHEMBL19976925 | 0.83 | TRPV1 (0.53) | MEN1KMT2ADHPSRAB9ANPC1 | |
| SCHEMBL19976903 | 0.82 | MEN1 (0.50) | PARP1MEN1KMT2AMAPK1RAB9A | |
| SCHEMBL16994046 | 0.82 | USP30 (0.61) | PARP1MEN1KMT2ADHPSMAPT | |
| SCHEMBL19977141 | 0.81 | DHPS (0.56) | PARP1DHPSMAPK1RAB9ANPC1 | |
| SCHEMBL19977090 | 0.78 | DHPS (0.46) | PARP1MEN1KMT2ADHPSMAPK1 | |
| SCHEMBL19976901 | 0.77 | GAA (0.59) | MEN1KMT2AMAPK1RAB9ANPC1 | |
| SCHEMBL19976946 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2AMAPTHSPA5HSPA9 | |
| SCHEMBL19976962 | 0.76 | TRPV1 (0.52) | MEN1KMT2AMAPK1TRPV1 | |
| SCHEMBL19976947 | 0.76 | MEN1 (0.53) | MEN1KMT2AMAPK1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |