Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCKAR | P32238 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977141 | 0.84 | DHPS (0.56) | DHPSMAPK1PARP1SMN1; SMN2TRPV1 | |
| SCHEMBL19977084 | 0.83 | DHPS (0.46) | DHPSMEN1KMT2AMAPK1PARP1 | |
| SCHEMBL19977044 | 0.83 | TRPV1 (0.53) | DHPSMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL19976949 | 0.82 | KMT2A (0.45) | MEN1KMT2ALMNASMN1; SMN2TRPV1 | |
| SCHEMBL16994015 | 0.82 | HPGDS (0.48) | CCKARITGB2ICAM1ITGAL | |
| SCHEMBL19976905 | 0.81 | KMT2A (0.56) | DHPSMEN1KMT2APOLB | |
| SCHEMBL19976985 | 0.80 | TRPV1 (0.52) | DHPSLMNASMN1; SMN2TRPV1HTT | |
| SCHEMBL19976913 | 0.79 | LMNA (0.43) | DHPSKMT2ALMNAHDAC3HDAC1 | |
| SCHEMBL19976906 | 0.78 | PGR (0.52) | MEN1KMT2AMAPK1LMNASMN1; SMN2 | |
| SCHEMBL19976914 | 0.78 | PARP1 (0.54) | DHPSMEN1KMT2AMAPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |