Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977035 | 0.88 | KMT2A (0.61) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19977046 | 0.87 | KMT2A (0.50) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19977032 | 0.86 | MAPT (0.55) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19976893 | 0.84 | SMN1; SMN2 (0.60) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19976994 | 0.83 | PGR (0.57) | KMT2AHTTMEN1RAB9AALOX12 | |
| SCHEMBL16994044 | 0.82 | CTSV (0.48) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL24862996 | 0.81 | KMT2A (0.45) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19977006 | 0.79 | APLNR (0.54) | KMT2AHTTSMN1; SMN2MEN1RAB9A | |
| SCHEMBL19977133 | 0.79 | HPGD (0.54) | KMT2AHTTMEN1RAB9AKDM4E | |
| SCHEMBL24862994 | 0.79 | HPGD (0.52) | KMT2AHTTSMN1; SMN2MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |