Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976916 | 0.87 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL19977035 | 0.87 | KMT2A (0.61) | KMT2ASMN1; SMN2HTTKDM4EL3MBTL1 | |
| SCHEMBL19977030 | 0.87 | MAPT (0.57) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL19976893 | 0.83 | SMN1; SMN2 (0.60) | KMT2ASMN1; SMN2HTTMEN1RAB9A | |
| SCHEMBL16993866 | 0.81 | ITGB1 (0.47) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL16999805 | 0.81 | ITGB1 (0.47) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL19976910 | 0.80 | PGR (0.52) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL19977006 | 0.78 | APLNR (0.54) | KMT2AALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL19976969 | 0.77 | ALDH1A1 (0.49) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL12780373 | 0.77 | KMT2A (0.66) | KMT2AALDH1A1SMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |