Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999811 | 0.83 | PSMB5 (0.46) | POLB | |
| SCHEMBL16994039 | 0.83 | PSMB5 (0.46) | POLB | |
| SCHEMBL19976937 | 0.82 | TP53 (0.52) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19977043 | 0.82 | MAPT (0.53) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19976915 | 0.81 | MEN1 (0.48) | KMT2AMEN1MAPTATRALOX15 | |
| SCHEMBL19976906 | 0.77 | PGR (0.52) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19976990 | 0.74 | KMT2A (0.60) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL19976954 | 0.73 | KMT2A (0.53) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL19977044 | 0.72 | TRPV1 (0.53) | KMT2AMEN1HTTSMN1; SMN2LMNA | |
| SCHEMBL1441735 | 0.72 | ATR (0.49) | HTTMAPTLMNATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |