Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 4/20 | 0.40 |
| ▸ | HSPA2 | P54652 | 2/20 | 0.40 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16993914 | 0.83 | HSPA5 (0.55) | ATRHSPA5HSPA2HSPA9MAPT | |
| SCHEMBL19977042 | 0.82 | KMT2A (0.52) | MEN1KMT2ARAB9ANPC1HSPA5 | |
| SCHEMBL19976988 | 0.82 | MEN1 (0.52) | MEN1KMT2ARAB9ANPC1HSPA5 | |
| SCHEMBL19976973 | 0.81 | KMT2A (0.44) | MEN1KMT2ARAB9AATRALDH1A1 | |
| SCHEMBL19976901 | 0.76 | GAA (0.59) | MEN1KMT2ARAB9ANPC1HSPA5 | |
| SCHEMBL19976931 | 0.73 | APLNR (0.72) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL19976952 | 0.73 | APLNR (0.57) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL19977006 | 0.73 | APLNR (0.54) | MEN1KMT2ARAB9AALDH1A1MAPK1 | |
| SCHEMBL19976925 | 0.72 | TRPV1 (0.53) | MEN1KMT2ARAB9ANPC1HSPA5 | |
| SCHEMBL1441735 | 0.72 | ATR (0.49) | ATRMAPK1MAPTKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |