Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976994 | 0.89 | PGR (0.57) | PGRSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19976943 | 0.87 | KMT2A (0.48) | KMT2AMEN1LMNAHTTHPGD | |
| SCHEMBL19977031 | 0.85 | KCNMA1 (0.54) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL19976910 | 0.84 | PGR (0.52) | PGRSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19977073 | 0.84 | PGR (0.52) | PGRSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19976990 | 0.83 | KMT2A (0.60) | KMT2AMEN1HTTHPGDKDM4E | |
| SCHEMBL19977024 | 0.83 | PGR (0.58) | PGRSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19976954 | 0.82 | KMT2A (0.53) | KMT2AMEN1LMNAHPGDKDM4E | |
| SCHEMBL19977133 | 0.82 | HPGD (0.54) | PGRSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL19977035 | 0.81 | KMT2A (0.61) | KMT2AMEN1LMNAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |