Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AGER | Q15109 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976990 | 0.91 | KMT2A (0.60) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19977009 | 0.84 | KMT2A (0.53) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19976970 | 0.83 | NPC1 (0.53) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL16994038 | 0.83 | PSMB5 (0.51) | KMT2AMEN1NPC1SMN1; SMN2 | |
| SCHEMBL19976906 | 0.82 | PGR (0.52) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19977035 | 0.81 | KMT2A (0.61) | KMT2AMEN1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL19977067 | 0.80 | CRHBP (0.60) | KMT2AMEN1NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19977032 | 0.80 | MAPT (0.55) | KMT2AMEN1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL19977133 | 0.80 | HPGD (0.54) | KMT2AMEN1NPC1ALDH1A1KDM4E | |
| SCHEMBL19976943 | 0.78 | KMT2A (0.48) | KMT2AMEN1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |