Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | MRGPRX1 | Q96LB2 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977047 | 0.91 | MRGPRX1 (0.45) | KMT2AMEN1MRGPRX1HPGDL3MBTL1 | |
| SCHEMBL19977009 | 0.88 | KMT2A (0.53) | KMT2AMEN1KDM4EHPGDLMNA | |
| SCHEMBL16999344 | 0.84 | PSMB5 (0.50) | KMT2AMEN1NPSR1NPC1 | |
| SCHEMBL16993921 | 0.84 | PSMB5 (0.50) | KMT2AMEN1NPSR1NPC1 | |
| SCHEMBL19976943 | 0.82 | KMT2A (0.48) | KMT2AMEN1KDM4EHPGDGAA | |
| SCHEMBL23594196 | 0.81 | MEN1 (0.46) | KMT2AMEN1MRGPRX1NPSR1NPC1 | |
| SCHEMBL19976990 | 0.78 | KMT2A (0.60) | KMT2AMEN1KDM4EHPGDL3MBTL1 | |
| SCHEMBL19976930 | 0.78 | ALDH1A1 (0.55) | KMT2AMEN1HPGDL3MBTL1GAA | |
| SCHEMBL19977067 | 0.77 | CRHBP (0.60) | KMT2AMEN1KDM4EHPGDL3MBTL1 | |
| SCHEMBL19977035 | 0.77 | KMT2A (0.61) | KMT2AMEN1KDM4EHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |