Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977009 | 0.90 | KMT2A (0.53) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19977032 | 0.88 | MAPT (0.55) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19977047 | 0.88 | MRGPRX1 (0.45) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL19976919 | 0.87 | LMNA (0.47) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL19977016 | 0.87 | ALDH1A1 (0.74) | ALDH1A1KMT2AMAPTMEN1POLB | |
| SCHEMBL19976942 | 0.85 | MEN1 (0.52) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL16999567 | 0.83 | PSMB5 (0.57) | ALDH1A1POLBNPSR1 | |
| SCHEMBL18261145 | 0.83 | PSMB5 (0.57) | ALDH1A1POLBNPSR1 | |
| SCHEMBL19977133 | 0.81 | HPGD (0.54) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL16999490 | 0.81 | PSMB5 (0.50) | ALDH1A1KMT2AMAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |