Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976896 | 0.91 | SMN1; SMN2 (0.47) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL19977128 | 0.84 | F2R (0.45) | ALDH1A1LMNAPOLBKDM4EMAPK1 | |
| SCHEMBL19977043 | 0.84 | MAPT (0.53) | ALDH1A1LMNAPOLBKDM4EMAPK1 | |
| SCHEMBL30767870 | 0.83 | PTGS2 (0.56) | ALDH1A1LMNAPOLBKDM4EMAPK1 | |
| SCHEMBL19977042 | 0.82 | KMT2A (0.52) | ALDH1A1LMNAPOLBKDM4EMAPK1 | |
| SCHEMBL18261148 | 0.82 | USP30 (0.52) | HPGD | |
| SCHEMBL16999363 | 0.82 | USP30 (0.52) | HPGD | |
| SCHEMBL19976912 | 0.76 | MRGPRX1 (0.48) | ALDH1A1LMNAPOLBKDM4EHPGD | |
| SCHEMBL19977069 | 0.76 | ALDH1A1 (0.57) | ALDH1A1LMNAPOLBHPGDSMN1; SMN2 | |
| SCHEMBL19976922 | 0.75 | HPGD (0.66) | ALDH1A1LMNAPOLBKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |