Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976988 | 0.91 | MEN1 (0.52) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30767860 | 0.85 | MEN1 (0.59) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL16994003 | 0.83 | HSPA5 (0.56) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19977005 | 0.82 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19976915 | 0.82 | MEN1 (0.48) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL19977128 | 0.78 | F2R (0.45) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19977043 | 0.78 | MAPT (0.53) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19976901 | 0.77 | GAA (0.59) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL19976903 | 0.75 | MEN1 (0.50) | KMT2AMEN1ALDH1A1HPGDNPSR1 | |
| SCHEMBL19976947 | 0.75 | MEN1 (0.53) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |