Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976922 | 0.85 | HPGD (0.66) | ALDH1A1SMN1; SMN2POLBKDM4EHTT | |
| SCHEMBL2330387 | 0.84 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2POLBKDM4EHTT | |
| SCHEMBL16999796 | 0.82 | LMNA (0.56) | ALDH1A1SMN1; SMN2POLBKDM4ELMNA | |
| SCHEMBL291032 | 0.80 | RAB9A (0.56) | ALDH1A1SMN1; SMN2HTTLMNAHDAC1 | |
| SCHEMBL7415328 | 0.80 | HDAC1 (0.63) | ALDH1A1SMN1; SMN2HTTLMNAHDAC1 | |
| SCHEMBL27518111 | 0.80 | HDAC1 (0.63) | ALDH1A1SMN1; SMN2HTTLMNAHDAC1 | |
| SCHEMBL19976974 | 0.80 | MEN1 (0.58) | ALDH1A1SMN1; SMN2POLBHTTLMNA | |
| SCHEMBL5216570 | 0.78 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2POLBKDM4EHTT | |
| SCHEMBL19976994 | 0.77 | PGR (0.57) | ALDH1A1POLBKDM4EHTTL3MBTL1 | |
| SCHEMBL19977075 | 0.77 | NPC1 (0.59) | ALDH1A1SMN1; SMN2KDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |