Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | SCN1A | P35498 | 1/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.58 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976994 | 0.88 | PGR (0.57) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976910 | 0.83 | PGR (0.52) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976906 | 0.83 | PGR (0.52) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19977073 | 0.83 | PGR (0.52) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL16999781 | 0.82 | POLB (0.51) | HPGDKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL19977133 | 0.81 | HPGD (0.54) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976922 | 0.79 | HPGD (0.66) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976956 | 0.78 | PGR (0.53) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19977069 | 0.77 | ALDH1A1 (0.57) | HPGDLMNAMAPTALDH1A1HTT | |
| SCHEMBL20366923 | 0.76 | SMN1; SMN2 (0.48) | HPGDLMNAGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |