Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | SCN1A | P35498 | 1/20 | 0.52 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976994 | 0.89 | PGR (0.57) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976911 | 0.87 | LMNA (0.54) | SMN1; SMN2ALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL19976969 | 0.85 | ALDH1A1 (0.49) | SMN1; SMN2HPGDALDH1A1LMNACYP1A2 | |
| SCHEMBL19977073 | 0.84 | PGR (0.52) | PGRSCN1ASCN2ASCN3ASMN1; SMN2 | |
| SCHEMBL19976906 | 0.84 | PGR (0.52) | PGRSCN1ASCN2ASCN3ASMN1; SMN2 | |
| SCHEMBL19977030 | 0.83 | MAPT (0.57) | SMN1; SMN2ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL19977024 | 0.83 | PGR (0.58) | PGRSCN1ASCN2ASCN3ASMN1; SMN2 | |
| SCHEMBL19977133 | 0.82 | HPGD (0.54) | PGRSCN1ASCN2ASCN3AHPGD | |
| SCHEMBL19976968 | 0.81 | KCNMA1 (0.57) | HPGDALDH1A1LMNAKDM4EHTT | |
| SCHEMBL19977046 | 0.80 | KMT2A (0.50) | SMN1; SMN2HPGDALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |