Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977046 | 0.87 | KMT2A (0.50) | MAPTSMN1; SMN2PYGLKMT2AMEN1 | |
| SCHEMBL19977032 | 0.86 | MAPT (0.55) | MAPTSMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL19976990 | 0.85 | KMT2A (0.60) | MAPTSMN1; SMN2PYGLKMT2AHDAC1 | |
| SCHEMBL19976910 | 0.83 | PGR (0.52) | MAPTSMN1; SMN2GAAPYGLKMT2A | |
| SCHEMBL19976980 | 0.82 | NPC1 (0.66) | MAPTPOLBKMT2AHDAC1MEN1 | |
| SCHEMBL18261161 | 0.82 | IDO1 (0.51) | MAPTSMN1; SMN2POLBGAARECQL | |
| SCHEMBL16999326 | 0.82 | IDO1 (0.51) | MAPTSMN1; SMN2POLBGAARECQL | |
| SCHEMBL19977133 | 0.81 | HPGD (0.54) | MAPTPOLBGAAKMT2AMEN1 | |
| SCHEMBL19976905 | 0.78 | KMT2A (0.56) | MAPTPOLBKMT2AMEN1METAP2 | |
| SCHEMBL19977016 | 0.78 | ALDH1A1 (0.74) | MAPTPOLBKMT2AMEN1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |