Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | METAP2 | P50579 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977067 | 0.88 | CRHBP (0.60) | ALDH1A1CRHBPCRHR2NPSR1L3MBTL1 | |
| SCHEMBL19976968 | 0.87 | KCNMA1 (0.57) | ALDH1A1NPSR1KMT2AMEN1KDM4E | |
| SCHEMBL19976930 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CRHBPCRHR2NPSR1L3MBTL1 | |
| SCHEMBL19977032 | 0.86 | MAPT (0.55) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL16993974 | 0.83 | ALDH1A1 (0.66) | ALDH1A1CRHBPCRHR2NPSR1L3MBTL1 | |
| SCHEMBL19976911 | 0.79 | LMNA (0.54) | ALDH1A1NPSR1KMT2AMEN1KDM4E | |
| SCHEMBL19977133 | 0.79 | HPGD (0.54) | ALDH1A1L3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL19976994 | 0.78 | PGR (0.57) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL19977030 | 0.78 | MAPT (0.57) | ALDH1A1KMT2AMEN1METAP2KDM4E | |
| SCHEMBL19977031 | 0.77 | KCNMA1 (0.54) | ALDH1A1NPSR1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |