Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 11/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977040 | 0.90 | MAPT (0.71) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL19976917 | 0.88 | ALDH1A1 (0.66) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL19976936 | 0.87 | SRPK1 (0.48) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL16993927 | 0.84 | HSPA1A (0.55) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL19977049 | 0.84 | ALDH1A1 (0.55) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL16993938 | 0.82 | MAPT (0.52) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL19976964 | 0.81 | L3MBTL1 (0.58) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL19977129 | 0.80 | ALDH1A1 (0.57) | MAPTNPSR1LMNATSHRMAPK1 | |
| SCHEMBL5558994 | 0.78 | POLB (0.66) | MAPTNPSR1TSHRMAPK1ALDH1A1 | |
| SCHEMBL19976901 | 0.77 | GAA (0.59) | MAPTNPSR1LMNATSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |