Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 8/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977129 | 0.88 | ALDH1A1 (0.57) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL19977130 | 0.88 | L3MBTL1 (0.44) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL19976995 | 0.88 | ALDH1A1 (0.48) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL19976959 | 0.87 | LMNA (0.59) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL19977049 | 0.85 | ALDH1A1 (0.55) | MAPTLMNAMAPK1ALDH1A1KMT2A | |
| SCHEMBL18261127 | 0.84 | L3MBTL1 (0.52) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL16999804 | 0.84 | L3MBTL1 (0.52) | L3MBTL1ATMMAPTLMNAMAPK1 | |
| SCHEMBL19977014 | 0.83 | ADRB1 (0.49) | LMNAMAPK1SMN1; SMN2KCNQ2ADRB1 | |
| SCHEMBL19977054 | 0.81 | MAPT (0.57) | MAPTLMNAMAPK1ALDH1A1KMT2A | |
| SCHEMBL5558994 | 0.80 | POLB (0.66) | L3MBTL1MAPTMAPK1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102193-B1 | ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES | UNIV RUTGERS (US) | 2023-01-11 | — | — | EP | disclosed |
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |