Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977007 | 0.86 | KMT2A (0.58) | SRPK1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL19976936 | 0.86 | SRPK1 (0.48) | SRPK1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL18261136 | 0.86 | HSPA1A (0.49) | SRPK1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL16999557 | 0.86 | HSPA1A (0.49) | SRPK1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL19976982 | 0.77 | L3MBTL1 (0.52) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL19977040 | 0.76 | MAPT (0.71) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL19977059 | 0.75 | KMT2A (0.58) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL23594204 | 0.74 | SMN1; SMN2 (0.45) | KMT2AMEN1NPSR1KDM4EALDH1A1 | |
| SCHEMBL23594111 | 0.74 | BACE1 (0.47) | KMT2ANPSR1ALDH1A1MAPTTSHR | |
| SCHEMBL16993961 | 0.74 | KMT2A (0.52) | SRPK1KMT2AMEN1NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |