Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976948 | 0.86 | KMT2A (0.58) | L3MBTL1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19977059 | 0.85 | KMT2A (0.58) | L3MBTL1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19976901 | 0.84 | GAA (0.59) | L3MBTL1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16993941 | 0.83 | CTSL (0.58) | L3MBTL1KMT2AMEN1HTTNPSR1 | |
| SCHEMBL16993972 | 0.81 | HSPA5 (0.48) | L3MBTL1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19976950 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1RAB9ANPC1HTT | |
| SCHEMBL19977007 | 0.80 | KMT2A (0.58) | L3MBTL1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL19976936 | 0.80 | SRPK1 (0.48) | KMT2AMEN1RAB9ANPC1NPSR1 | |
| SCHEMBL19976919 | 0.80 | LMNA (0.47) | KMT2AMEN1RAB9AHTTNPSR1 | |
| SCHEMBL19976943 | 0.79 | KMT2A (0.48) | KMT2AMEN1RAB9AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |