Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.51 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976936 | 0.89 | SRPK1 (0.48) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19976917 | 0.87 | ALDH1A1 (0.66) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19977060 | 0.86 | SRPK1 (0.50) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16993961 | 0.85 | KMT2A (0.52) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19976996 | 0.84 | LMNA (0.53) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19977056 | 0.83 | KDM4E (0.59) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19977098 | 0.82 | KDM4E (0.51) | KMT2AKDM4EALDH1A1HTTMEN1 | |
| SCHEMBL19976982 | 0.80 | L3MBTL1 (0.52) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19977040 | 0.78 | MAPT (0.71) | KMT2ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL19977059 | 0.77 | KMT2A (0.58) | KMT2ANPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |