Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976945 | 0.85 | SMN1; SMN2 (0.57) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL16999304 | 0.84 | GPR132 (0.58) | ALDH1A1KMT2ATSHRMEN1RAB9A | |
| SCHEMBL19976956 | 0.83 | PGR (0.53) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL19976974 | 0.82 | MEN1 (0.58) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL19976922 | 0.80 | HPGD (0.66) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL13753371 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL13754286 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL13761465 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL13753419 | 0.76 | ALDH1A1 (0.70) | ALDH1A1KMT2ATSHRMEN1NPC1 | |
| SCHEMBL13754276 | 0.75 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |