Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977074 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2GAAKMT2AMEN1GPR139 | |
| SCHEMBL19976974 | 0.83 | MEN1 (0.58) | SMN1; SMN2GAAKMT2AMEN1MAPT | |
| SCHEMBL16999314 | 0.83 | GPR139 (0.55) | SMN1; SMN2GAANPSR1KMT2AMEN1 | |
| SCHEMBL19976922 | 0.81 | HPGD (0.66) | SMN1; SMN2GAAMAPTRAB9ALMNA | |
| SCHEMBL19976956 | 0.79 | PGR (0.53) | GAAKMT2AMEN1MAPTRAB9A | |
| SCHEMBL19976893 | 0.77 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1TSHRRAB9A | |
| SCHEMBL4117223 | 0.76 | DDX3X (0.69) | SMN1; SMN2NPSR1KMT2AMEN1MAPT | |
| SCHEMBL19976955 | 0.75 | POLB (0.53) | SMN1; SMN2GAATSHRMAPTRAB9A | |
| SCHEMBL19976916 | 0.74 | KMT2A (0.51) | SMN1; SMN2NPSR1KMT2AMEN1TSHR | |
| SCHEMBL19977019 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2GAAMAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |