Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MDM4 | O15151 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977071 | 0.90 | LMNA (0.45) | SMN1; SMN2LMNAKMT2AGFERTP53 | |
| SCHEMBL19977124 | 0.83 | SMN1; SMN2 (0.62) | SMN1; SMN2LMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL19976922 | 0.81 | HPGD (0.66) | SMN1; SMN2LMNAGFERPOLBHPGD | |
| SCHEMBL19977072 | 0.81 | LMNA (0.54) | SMN1; SMN2LMNAKMT2AGFERPOLB | |
| SCHEMBL19976893 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2APOLBHPGDMEN1 | |
| SCHEMBL16999521 | 0.79 | CTSL (0.55) | — | |
| SCHEMBL19977069 | 0.79 | ALDH1A1 (0.57) | SMN1; SMN2LMNAPOLBHPGDALDH1A1 | |
| SCHEMBL19977018 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKMT2AGFERPOLB | |
| SCHEMBL19976955 | 0.78 | POLB (0.53) | SMN1; SMN2LMNATP53POLBHPGD | |
| SCHEMBL19976980 | 0.78 | NPC1 (0.66) | LMNAKMT2APOLBHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |