Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032597 | 0.87 | ALDH1A1 (0.43) | ALDH1A1KMT2ATSHRTDP1L3MBTL1 | |
| SCHEMBL3124100 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2ALMNAHTTTSHR | |
| SCHEMBL2034400 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRNOS1NOS2 | |
| SCHEMBL29287973 | 0.79 | DGAT1 (0.32) | ALDH1A1 | |
| SCHEMBL18232027 | 0.79 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNATSHRMEN1 | |
| SCHEMBL283370 | 0.79 | — | — | |
| SCHEMBL3015419 | 0.77 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAHTTTSHR | |
| SCHEMBL28287867 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2ALMNAHTTTSHR | |
| SCHEMBL277359 | 0.76 | ALDH1A1 (0.34) | ALDH1A1KMT2ALMNAHTT | |
| SCHEMBL10373136 | 0.73 | MEN1 (0.31) | ALDH1A1KMT2AMEN1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079772-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079772-A1 | SALTS OF HIV INHIBITOR COMPOUNDS | SAMHD1, ZC3HAV1, CCR5 | ALDH1A1 3475/4885KMT2A 2839/4885LMNA 3573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.