SCHEMBL277359

SCHEMBL277359

CCC(O)(COC=O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18176761 0.87 ALDH1A1 (0.40) ALDH1A1
SCHEMBL9609678 0.79 ALDH1A1 (0.56) ALDH1A1LMNA
SCHEMBL19977438 0.76 ALDH1A1 (0.39) ALDH1A1LMNAHTTKMT2A
SCHEMBL18561743 0.75 CYP2D6 (0.38)
SCHEMBL13055293 0.74 TET2 (0.39) ALDH1A1
SCHEMBL283370 0.74
SCHEMBL26852304 0.73
SCHEMBL5365915 0.72
SCHEMBL28287867 0.71 ALDH1A1 (0.48) ALDH1A1LMNAHTTKMT2A
SCHEMBL5752283 0.71 ACLY (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230364247-A1 NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS THE JOHNS HOPKINS UNIVERSITY 2023-11-16 US disclosed
US-11660349-B2 Non-linear multiblock copolymer-drug conjugates for the delivery of active agents THE JOHNS HOPKINS UNIVERSITY (US) 2023-05-30 US disclosed
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES CLARIA ODIN LLC 2018-02-01 US disclosed
US-8349783-B2 Treatment methods using disinfecting compositions containing a polymer complex of organic acid RECKITT BENCKISER LLC (US) 2013-01-08 US disclosed
US-8133855-B2 Environmentally acceptable dilutable hard surface treatment compositions RECKITT BENCKISER LLC (US) 2012-03-13 US disclosed
US-20120027717-A1 TREATMENT METHODS USING DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF ORGANIC ACID RECKITT BENCKISER LLC. (US) 2012-02-02 US disclosed
US-20110098210-A1 Environmentally Acceptable Dilutable Hard Surface Treatment Compositions Morris Corporate Center IV (US) 2011-04-28 US disclosed
US-20110053945-A1 SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHY-DRO-5H-PYRROLO[3,4-B]PYRAZINE SEPRACOR INC. (US) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11660349-B2 Non-linear multiblock copolymer-drug conjugates for the delivery of active agents VEGFA, UACA, PDE6A ALDH1A1 1084/4885LMNA 1968/4885HTT 1687/4885
US-20110053945-A1 SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHY-DRO-5H-PYRROLO[3,4-B]PYRAZINE MDH2, SLC25A11, MDH1 ALDH1A1 503/4885LMNA 4874/4885HTT 3656/4885
US-20230364247-A1 NON-LINEAR MULTIBLOCK COPOLYMER-DRUG CONJUGATES FOR THE DELIVERY OF ACTIVE AGENTS VEGFA, UACA, PDE6A ALDH1A1 1084/4885LMNA 1968/4885HTT 1687/4885
US-20180028647-A1 MODIFICATIONS OF THERAPEUTIC AGENTS FOR ENHANCED DELIVERY TO TARGET SITES PDK1, PC, PDK2 ALDH1A1 1505/4885LMNA 2585/4885HTT 210/4885
US-20120027717-A1 TREATMENT METHODS USING DISINFECTING COMPOSITIONS CONTAINING A POLYMER COMPLEX OF ORGANIC ACID POLR1C, AOC1, HAO2 ALDH1A1 598/4885LMNA 3599/4885HTT 3252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.