Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977779 | 0.95 | AHR (0.37) | AHRKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL19977913 | 0.85 | KDM4E (0.30) | KDM4E | |
| SCHEMBL19977883 | 0.83 | KDM4E (0.30) | KDM4E | |
| SCHEMBL23184304 | 0.82 | AHR (0.43) | AHRKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL19977933 | 0.81 | AHR (0.34) | AHR | |
| SCHEMBL30972504 | 0.80 | HDAC6 (0.40) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL15030784 | 0.80 | HDAC6 (0.40) | MEN1ALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL19977780 | 0.80 | — | — | |
| SCHEMBL17752249 | 0.80 | MAOA (0.42) | KDM4EMEN1ALDH1A1MAPTHPGD | |
| SCHEMBL19977797 | 0.79 | GPR3 (0.33) | ALDH1A1MAPTHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | AHR 1991/4885KDM4E 2668/4885MEN1 1489/4885 |
| US-20180083198-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME | NR2E3, CRY1, ERG | AHR 771/4885KDM4E 2931/4885MEN1 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.