SCHEMBL19978070

SCHEMBL19978070

c1ccc2c(c1)oc1c3cccc4c5oc6ccccc6c5c5ccc(c21)n5c34

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.38
KDM5A P29375 1/20 0.37
KDM4E B2RXH2 3/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
HPGD P15428 2/20 0.36
CASP7 P55210 2/20 0.36
HSD17B10 Q99714 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MEN1 O00255 1/20 0.36
ALPI P09923 1/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
CASP3 P42574 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36
CASP6 P55212 1/20 0.36
KMT2A Q03164 1/20 0.36
MCL1 Q07820 1/20 0.36
ALDH1A1 P00352 4/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19978069 0.94 MAOA (0.34) MAOAKDM5AKDM4ECYP3A4MAPT
SCHEMBL21717878 0.90 ALOX5 (0.39) MAOAKDM5AKDM4ECYP3A4MAPT
SCHEMBL21718195 0.86 MAPT (0.35) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL23995597 0.84 MEN1 (0.35) MAOAKDM5AKDM4ECYP3A4MAPT
SCHEMBL24117553 0.83 ALOX5 (0.37) MAOAKDM5AKDM4ECYP3A4MAPT
SCHEMBL21889620 0.83 ALOX5 (0.38) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL19978066 0.83 L3MBTL1 (0.38) MAOAKDM5AKDM4ECYP3A4MAPT
SCHEMBL21718159 0.82 ALDH1A1 (0.39) MAOAKDM4ECYP3A4MAPTHPGD
SCHEMBL21717973 0.82 L3MBTL1 (0.43) MAOACYP3A4HPGDCASP7HSD17B10
SCHEMBL19978060 0.80 MAOA (0.34) MAOAKDM5AKDM4ECYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083203-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-03-22 US disclosed
US-20180083203-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180083203-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NES, CACNA2D4, PGLS MAOA 904/4885KDM5A 3305/4885KDM4E 2755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.