Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978239 | 0.79 | MAPT (0.47) | KDM4EMEN1KMT2ACYP1A2ERN1 | |
| SCHEMBL4856328 | 0.72 | MEN1 (0.56) | KDM4EMEN1KMT2ACYP1A2ALDH1A1 | |
| Iodide SCHEMBL29763642 | 0.71 | MEN1 (0.54) | KDM4EMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL10111830 | 0.70 | MEN1 (0.38) | MEN1KMT2ACYP1A2ALDH1A1MAPT | |
| SCHEMBL28795459 | 0.67 | KMT2A (0.49) | KDM4EMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL28705484 | 0.67 | NCOA3 (0.38) | KDM4EMEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL21235344 | 0.66 | NFATC1 (0.39) | GPR3KDM4ECYP1A2GRM4TGFBR1 | |
| SCHEMBL4255042 | 0.65 | MPL (0.40) | MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL17971386 | 0.64 | KDM4E (0.40) | GPR3KDM4ETLR7TOP2AERN1 | |
| SCHEMBL10111810 | 0.64 | LPL (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-02-11 | — | — | US | disclosed |
| US-10633542-B2 | Azacyanine dyes and use thereof | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2020-04-28 | — | — | US | disclosed |
| WO-2019180475-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2019-09-26 | — | — | WO | disclosed |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INTRACE MEDICAL SA (CH) | 2019-09-26 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | GPR3 1105/4885KDM4E 783/4885MEN1 541/4885 |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | GPR3 1105/4885KDM4E 783/4885MEN1 541/4885 |
| US-10633542-B2 | Azacyanine dyes and use thereof | INMT, AZI2, MYADM | GPR3 1105/4885KDM4E 783/4885MEN1 541/4885 |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | GPR3 1105/4885KDM4E 783/4885MEN1 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.