Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.35 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10111830 | 0.76 | MEN1 (0.38) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL4255042 | 0.71 | MPL (0.40) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10111810 | 0.70 | LPL (0.33) | MEN1KMT2A | |
| SCHEMBL4856328 | 0.69 | MEN1 (0.56) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL13609739 | 0.69 | MEN1 (0.33) | MEN1KMT2A | |
| Iodide SCHEMBL29763642 | 0.68 | MEN1 (0.54) | MEN1KMT2ATSHRKDM4EALDH1A1 | |
| SCHEMBL15895348 | 0.68 | IMPDH2 (0.36) | NCOA3IMPDH2IMPDH1TSHRAR | |
| SCHEMBL19978243 | 0.67 | GPR3 (0.39) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL15895263 | 0.66 | NCOA3 (0.35) | NCOA3IMPDH2IMPDH1TSHRAR | |
| SCHEMBL7813270 | 0.65 | TSHR (0.46) | NCOA3MEN1KMT2AIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874197-A | Viscosity fluorescent probe capable of targeting various organelles | 郑州大学 | 2022-08-09 | — | — | CN | claimed |
| CN-114133387-A | Fluorescent probe with viscosity sensing property and capable of targeting multiple organelles | 郑州大学 | 2022-03-04 | — | — | CN | claimed |
| CN-114874197-A | Viscosity fluorescent probe capable of targeting various organelles | 郑州大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-114133387-A | Fluorescent probe with viscosity sensing property and capable of targeting multiple organelles | 郑州大学 | 2022-03-04 | — | — | CN | disclosed |