SCHEMBL19979018

SCHEMBL19979018

Clc1ccc(-c2ccc([Si](c3ccccc3)(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
GAA P10253 2/20 0.47
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TSHR P16473 1/20 0.46
AHR P35869 1/20 0.44
NPC1 O15118 4/20 0.44
RAB9A P51151 4/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CTRC Q99895 1/20 0.42
MAP4K4 O95819 1/20 0.42
ALDH1A1 P00352 1/20 0.41
ALDH1A3 P47895 1/20 0.41
SCN2A Q99250 1/20 0.40
AKT1 P31749 1/20 0.40
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15661564 0.93 TSHR (0.53) CYP1A2GAALMNAKDM4EL3MBTL1
SCHEMBL15975759 0.87 ALDH1A1 (0.47) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL2005519 0.87 ALDH1A1 (0.47) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL3292244 0.87 ALDH1A1 (0.47) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL31506387 0.86 CYP1A2 (0.52) CYP1A2GAALMNAKDM4EL3MBTL1
SCHEMBL3889979 0.85 ALDH1A1 (0.53) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL28720090 0.85 ALDH1A1 (0.53) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL9319701 0.85 ALDH1A1 (0.53) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL18682233 0.85 ALDH1A1 (0.53) CYP1A2NPC1RAB9AMEN1KMT2A
SCHEMBL20427762 0.82 CES2 (0.42) CYP1A2LMNAKDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345817-A1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2023-10-26 US disclosed
EP-4198104-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2023-06-21 EP disclosed
CN-115885022-A Organic electroluminescent element 保土谷化学工业株式会社 2023-03-31 CN disclosed
US-11165029-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2021-11-02 US disclosed
US-10777747-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-15 US disclosed
US-10777747-B2 Amine compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-09-15 US disclosed
US-20180159046-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180159046-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180159046-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180083209-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083209-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180159046-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME PNMT, PIEZO1, ODC1 CYP1A2 1580/4885GAA 1897/4885LMNA 2933/4885
US-20180083209-A1 AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME PNMT, PIEZO1, ODC1 CYP1A2 1812/4885GAA 2746/4885LMNA 2636/4885
US-20230345817-A1 ORGANIC ELECTROLUMINESCENT DEVICE SLC7A5, SLC43A1, SLCO4C1 CYP1A2 849/4885GAA 1230/4885LMNA 1898/4885
US-11165029-B2 Amine compound and organic electroluminescence device including the same PNMT, PIEZO1, ODC1 CYP1A2 1812/4885GAA 2746/4885LMNA 2636/4885
US-10777747-B2 Amine compound and organic electroluminescence device including the same PNMT, PIEZO1, ODC1 CYP1A2 1592/4885GAA 1849/4885LMNA 2880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.