Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | S100B | P04271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212937 | 0.85 | KDM4E (0.36) | HDAC3HDAC2HDAC1S100B | |
| SCHEMBL24405403 | 0.79 | S100B (0.51) | HDAC1S100B | |
| SCHEMBL19980947 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL24405348 | 0.72 | S100B (0.38) | HDAC1S100B | |
| SCHEMBL8379952 | 0.72 | HDAC1 (0.47) | HDAC3HDAC2HDAC1 | |
| SCHEMBL15244180 | 0.70 | HDAC1 (0.45) | HDAC3HDAC2HDAC1 | |
| SCHEMBL19980976 | 0.69 | HDAC1 (0.41) | HDAC3HDAC2HDAC1 | |
| SCHEMBL8943196 | 0.69 | HDAC1 (0.49) | HDAC3HDAC2NCOR1HDAC8HDAC1 | |
| SCHEMBL22476593 | 0.68 | HDAC1 (0.40) | HDAC3HDAC2NCOR1HDAC8HDAC1 | |
| SCHEMBL24006345 | 0.68 | HDAC1 (0.45) | HDAC3HDAC2NCOR1HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |