Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 8/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | S100B | P04271 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980897 | 0.94 | HDAC1 (0.40) | HDAC1HDAC2HDAC3HPGDTSHR | |
| SCHEMBL18633372 | 0.84 | THRB (0.37) | HDAC1HDAC2HDAC3MAPTKDM4E | |
| SCHEMBL19903974 | 0.83 | S100B (0.55) | S100BMAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL19980984 | 0.83 | HDAC1 (0.40) | HDAC1HDAC2HDAC3KDM4EALDH1A1 | |
| SCHEMBL6075087 | 0.81 | S100B (0.51) | HDAC1HDAC2HDAC3S100BMAPT | |
| SCHEMBL19980976 | 0.80 | HDAC1 (0.41) | HDAC1HDAC2HDAC3TSHRPOLB | |
| SCHEMBL21117538 | 0.79 | BTK (0.37) | HDAC1HDAC2MAPTKDM4EHPGD | |
| SCHEMBL19904030 | 0.79 | TSHR (0.49) | MAPTKDM4ELMNAHPGDTSHR | |
| SCHEMBL22212876 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2HDAC3TSHR | |
| SCHEMBL19980935 | 0.77 | THRB (0.36) | S100BMAPTKDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |