Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980897 | 0.87 | HDAC1 (0.40) | THRBHDAC3HDAC2HPGDTSHR | |
| SCHEMBL19980955 | 0.84 | HDAC1 (0.38) | HDAC3HDAC2HPGDTSHRPOLB | |
| SCHEMBL19980984 | 0.84 | HDAC1 (0.40) | THRBHDAC3HDAC2GAAHDAC1 | |
| SCHEMBL19980988 | 0.82 | THRB (0.43) | THRBHDAC3HDAC2HPGDTSHR | |
| SCHEMBL19980987 | 0.82 | MTNR1B (0.35) | HDAC3HDAC2NCOR1HDAC8MAPK1 | |
| SCHEMBL21117673 | 0.81 | HDAC1 (0.32) | HDAC3HDAC2HDAC1 | |
| SCHEMBL21117538 | 0.81 | BTK (0.37) | THRBHDAC2HPGDTSHRGAA | |
| SCHEMBL19980935 | 0.76 | THRB (0.36) | THRBHPGDTSHRGAAKDM4E | |
| SCHEMBL19903974 | 0.75 | S100B (0.55) | THRBHPGDTSHRMAPK1KDM4E | |
| SCHEMBL18633371 | 0.75 | ALDH1A1 (0.35) | HPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984114-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |