Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | SCN1A | P35498 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19904093 | 0.94 | S100B (0.55) | S100BTDP1HTTPOLBAPEX1 | |
| SCHEMBL19980976 | 0.83 | HDAC1 (0.41) | TDP1HTTPOLBAPEX1THRB | |
| SCHEMBL19980921 | 0.82 | PHLPP2 (0.44) | TDP1HTTPOLBAPEX1THRB | |
| SCHEMBL3192372 | 0.80 | CA1 (0.43) | TDP1HTTPOLBAPEX1THRB | |
| SCHEMBL21117572 | 0.80 | S100B (0.43) | S100BTHRBTSHRHIF1AALDH1A1 | |
| SCHEMBL19981012 | 0.80 | HDAC1 (0.33) | TDP1HTTPOLBAPEX1THRB | |
| SCHEMBL19980985 | 0.79 | HDAC1 (0.38) | TSHR | |
| SCHEMBL19980755 | 0.78 | S100B (0.47) | S100BHTTTSHRCYP2D6HRH3 | |
| SCHEMBL3192908 | 0.77 | THRB (0.41) | TDP1HTTPOLBAPEX1THRB | |
| SCHEMBL19981017 | 0.77 | PHLPP2 (0.40) | TDP1HTTPOLBAPEX1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |