Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981137 | 0.92 | S1PR1 (0.38) | CTSAS1PR1NPSR1MAPTL3MBTL1 | |
| SCHEMBL19981316 | 0.79 | ALDH1A1 (0.45) | S1PR1NPSR1MAPTL3MBTL1ALDH1A1 | |
| SCHEMBL19981269 | 0.78 | CTSA (0.45) | CTSALMNATSHR | |
| SCHEMBL19981248 | 0.77 | CTSA (0.47) | CTSALMNATSHR | |
| SCHEMBL18077943 | 0.75 | VSIR (0.48) | CTSAS1PR1 | |
| SCHEMBL19867021 | 0.75 | VSIR (0.48) | CTSAS1PR1 | |
| SCHEMBL19871036 | 0.72 | GPR88 (0.42) | NPSR1PPARDPPARAALDH1A1LMNA | |
| SCHEMBL18078189 | 0.71 | VSIR (0.55) | NPSR1MAPTPPARDPPARAALDH1A1 | |
| SCHEMBL18078154 | 0.71 | VSIR (0.55) | NPSR1MAPTPPARDPPARAALDH1A1 | |
| SCHEMBL19981240 | 0.70 | LMNA (0.40) | CTSAS1PR1MAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |