Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19981130 | 0.92 | CTSA (0.41) | S1PR1LMNANPSR1TSHRALDH1A1 | |
| SCHEMBL19981316 | 0.78 | ALDH1A1 (0.45) | S1PR1LMNANPSR1TSHRALDH1A1 | |
| SCHEMBL19981233 | 0.77 | LMNA (0.44) | S1PR1HDAC6LMNATSHRCTSA | |
| SCHEMBL18077932 | 0.76 | VSIR (0.43) | S1PR1HDAC6LMNATSHRCTSA | |
| SCHEMBL19867036 | 0.76 | VSIR (0.43) | S1PR1HDAC6LMNATSHRCTSA | |
| SCHEMBL19981269 | 0.70 | CTSA (0.45) | LMNATSHRCTSA | |
| SCHEMBL24218494 | 0.69 | LMNA (0.45) | S1PR1HDAC6LMNATSHRCTSA | |
| SCHEMBL19981248 | 0.68 | CTSA (0.47) | HDAC6LMNATSHRCTSA | |
| SCHEMBL19871036 | 0.68 | GPR88 (0.42) | LMNANPSR1TSHRALDH1A1HPGD | |
| SCHEMBL19867021 | 0.67 | VSIR (0.48) | S1PR1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |