Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173652 | 0.75 | ALDH1A1 (0.38) | DGAT1 | |
| SCHEMBL25697451 | 0.75 | NPC1 (0.35) | DGAT1 | |
| SCHEMBL160484 | 0.71 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL168671 | 0.71 | CCNA2 (0.38) | — | |
| SCHEMBL25219333 | 0.69 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1392686 | 0.68 | ROCK2 (0.35) | — | |
| SCHEMBL31381549 | 0.67 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25408348 | 0.66 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL29109010 | 0.65 | KDM4E (0.34) | DGAT1 | |
| SCHEMBL31022044 | 0.64 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |