Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 4/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982261 | 0.91 | LMNA (0.51) | ALDH1A1RAB9AACELMNAHTT | |
| SCHEMBL22929113 | 0.81 | ACE (0.46) | ALDH1A1RAB9AACESMN1; SMN2TP53 | |
| SCHEMBL19982125 | 0.80 | YAP1 (0.57) | ACEYAP1GAA | |
| SCHEMBL19982079 | 0.78 | YAP1 (0.73) | YAP1GAA | |
| SCHEMBL19975033 | 0.73 | YAP1 (0.62) | ALDH1A1RAB9AYAP1LMNAGAA | |
| SCHEMBL19975035 | 0.73 | YAP1 (0.62) | ALDH1A1RAB9AYAP1LMNAGAA | |
| SCHEMBL20111166 | 0.72 | HDAC1 (0.61) | ALDH1A1SMN1; SMN2CHRNB2CHRNA5CHRNA7 | |
| SCHEMBL8189803 | 0.72 | KMT2A (0.58) | ALDH1A1SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL22929115 | 0.71 | ITGB1 (0.46) | ALDH1A1ACELTA4HKDM4E | |
| SCHEMBL1302762 | 0.71 | SMN1; SMN2 (0.57) | ALDH1A1RAB9ASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053446-A1 | YAP1 INHIBITORS THAT TARGET THE INTERACTION OF YAP1 WITH OCT4 | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2018-03-22 | — | — | WO | disclosed |