SCHEMBL19982616

SCHEMBL19982616

Cc1cc(CCP(=O)(O)O)cc(I)c1Oc1ccc(O)c(C(C)C)c1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 19/20 0.70
THRA P10827 18/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL282015 0.93 THRB (0.79) THRBTHRA
SCHEMBL13867752 0.92 THRA (0.78) THRBTHRA
SCHEMBL21291323 0.89 THRB (0.87) THRBTHRA
SCHEMBL13381606 0.86 THRB (0.73) THRBTHRA
SCHEMBL282175 0.86 THRA (0.75) THRBTHRA
SCHEMBL3160909 0.82 THRA (1.00) THRBTHRA
SCHEMBL282331 0.82 THRB (1.00) THRBTHRA
SCHEMBL21291280 0.82 THRB (0.87) THRBTHRA
SCHEMBL13574304 0.81 THRB (0.68) THRBTHRA
SCHEMBL285715 0.81 THRA (1.00) THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220016136-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS VIKING THERAPEUTICS, INC. 2022-01-20 US disclosed
US-20220016137-A1 COMPOSITIONS FOR THE TREATMENT OF FIBROSIS AND INFLAMMATION VIKING THERAPEUTICS, INC. 2022-01-20 US disclosed
WO-2018053036-A1 METHOD OF REDUCING THYROID-ASSOCIATED SIDE EFFECTS VIKING THERAPEUTICS, INC. (US) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220016136-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIVER DISORDERS FABP1, SLC10A1, TSHR THRB 7/4885THRA 8/4885
US-20220016137-A1 COMPOSITIONS FOR THE TREATMENT OF FIBROSIS AND INFLAMMATION COL2A1, COL1A1, TGFBR2 THRB 30/4885THRA 187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.