Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29077427 | 0.98 | PARP1 (0.47) | PARP1POLBMEN1KMT2ATSHR | |
| SCHEMBL13653935 | 0.84 | MAOB (0.48) | POLBMEN1KMT2AMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL28856154 | 0.82 | MAOB (0.47) | POLBMEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL14670993 | 0.82 | ALDH1A1 (0.42) | TSHRSIGMAR1 | |
| SCHEMBL13724974 | 0.82 | ALDH1A1 (0.43) | MEN1KMT2AMAPTCYP2C19TDP1 | |
| SCHEMBL27544567 | 0.79 | SIGMAR1 (0.42) | MEN1KMT2ACYP2C19TDP1SIGMAR1 | |
| SCHEMBL28617157 | 0.79 | PARP1 (0.57) | PARP1POLBMEN1KMT2ATSHR | |
| SCHEMBL15714872 | 0.78 | LOXL2 (0.47) | POLBMEN1KMT2ATSHRMAPT | |
| SCHEMBL19983030 | 0.78 | HDAC8 (0.53) | POLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL1565391 | 0.77 | PARP1 (0.55) | PARP1POLBMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4526291-A1 | INDUCERS OF INTEGRATED STRESS RESPONSE TO TREAT CANCER | The Board of Regents of the University of Texas System (US) | 2025-03-26 | — | — | EP | disclosed |
| EP-4306166-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Aquinnah Pharmaceuticals Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| CN-109983012-B | Ketone inhibitors of lysine gum protease | 莱特豪斯制药公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-111698989-B | Heterocyclic substituted pyridine derivatives as antifungal agents | 安普利克斯制药公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |