Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13653935 | 0.84 | MAOB (0.48) | ALDH1A1CA1CA2CA9CA12 | |
| SCHEMBL15397823 | 0.83 | TP53 (0.38) | TP53PTGS2CA1CA2CA9 | |
| SCHEMBL19983141 | 0.82 | PARP1 (0.48) | TSHRSIGMAR1 | |
| SCHEMBL13724974 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PTGS2RIPK1 | |
| Hydrochloric Acid SCHEMBL28856154 | 0.82 | MAOB (0.47) | ALDH1A1CA1CA2CA9CA12 | |
| Hydrochloric Acid SCHEMBL29077427 | 0.81 | PARP1 (0.47) | TSHRSIGMAR1 | |
| SCHEMBL10478230 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHR | |
| SCHEMBL15714872 | 0.78 | LOXL2 (0.47) | ALDH1A1TSHRTP53CA1CA2 | |
| SCHEMBL19983030 | 0.78 | HDAC8 (0.53) | ALDH1A1PTGS2RIPK1HDAC1HDAC2 | |
| SCHEMBL13283358 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106167474-A | A kind of preparation method of A Qitasai | 中国医学科学院药物研究所 | 2016-11-30 | — | — | CN | claimed |
| CN-117597801-A | Conductive substrate for battery electrode and method for manufacturing same | JSR株式会社 | 2024-02-23 | — | — | CN | disclosed |
| WO-2023282228-A1 | CONDUCTIVE SUBSTRATE FOR BATTERY ELECTRODES AND METHOD FOR PRODUCING SAME | JSR株式会社 | 2023-01-12 | — | — | WO | disclosed |
| CN-115139587-A | Electromagnetic wave shielding laminate and method for manufacturing same, shielded printed wiring board and method for manufacturing same, semiconductor package, and electronic device | JSR株式会社 | 2022-10-04 | — | — | CN | disclosed |
| WO-2022181380-A1 | SURFACE TREATMENT METHOD, SURFACE TREATEMENT AGENT, METHOD FOR PRODUCING BONDED BODY, METHOD FOR PRODUCING SUBSTANCE HAVING CONDUCTOR COATING, METHOD FOR PRODUCING SUBSTANCE ON WHICH COATING FILM IS FORMED, METHOD FOR PRODUCING CONDUCTOR-COATED RESIN SUBSTRATE, METHOD FOR PRODUCING WAVEGUID, METHOD FOR PRODUCING CIRCUIT BOARD OR ANTENNA, AND COMPOUND | JSR株式会社 | 2022-09-01 | — | — | WO | disclosed |
| WO-2022181380-A1 | SURFACE TREATMENT METHOD, SURFACE TREATEMENT AGENT, METHOD FOR PRODUCING BONDED BODY, METHOD FOR PRODUCING SUBSTANCE HAVING CONDUCTOR COATING, METHOD FOR PRODUCING SUBSTANCE ON WHICH COATING FILM IS FORMED, METHOD FOR PRODUCING CONDUCTOR-COATED RESIN SUBSTRATE, METHOD FOR PRODUCING WAVEGUID, METHOD FOR PRODUCING CIRCUIT BOARD OR ANTENNA, AND COMPOUND | JSR株式会社 | 2022-09-01 | — | — | WO | disclosed |
| US-11332464-B2 | Inhibitors of lysine gingipain | Cortexyme, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-11332464-B2 | Inhibitors of lysine gingipain | Cortexyme, Inc. (US) | 2022-05-17 | — | — | US | disclosed |
| US-10906881-B2 | Inhibitors of arginine gingipain | Cortexyme, Inc. (US) | 2021-02-02 | — | — | US | disclosed |
| US-10906881-B2 | Inhibitors of arginine gingipain | Cortexyme, Inc. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20160096830-A1 | INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2016-04-07 | — | — | US | disclosed |
| US-20160096830-A1 | INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2016-04-07 | — | — | US | disclosed |
| US-9167820-B2 | Anti-biofilm compounds | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-9167820-B2 | Anti-biofilm compounds | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2015-10-27 | — | — | US | disclosed |
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION INC. (US) | 2014-06-12 | — | — | US | disclosed |
| CN-103420954-A | Preparation technology for aziditaxel and correlated intermediates thereof | INST MATERIA MEDICA CAMS | 2013-12-04 | — | — | CN | disclosed |
| WO-2013016206-A1 | ANTI-BIOFILM COMPOUNDS | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) | 2013-01-31 | — | — | WO | disclosed |
| CN-1199954-C | Benzodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 2005-05-04 | — | — | CN | disclosed |
| CN-1379764-A | Benzodiazepine derivatives | HOFFMANN LA ROCHE (CH) | 2002-11-13 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10906881-B2 | Inhibitors of arginine gingipain | ARGLU1, ENPEP, PRAP1 | ALDH1A1 2785/4885TSHR 3609/4885TP53 704/4885 |
| US-20140161845-A1 | ANTI-BIOFILM COMPOUNDS | MSR1, NPR1, FPR1 | ALDH1A1 3602/4885TSHR 123/4885TP53 4671/4885 |
| US-20160096830-A1 | INHIBITORS OF LYSINE GINGIPAIN | ENPEP, PHYKPL, PREP | ALDH1A1 2355/4885TSHR 4691/4885TP53 1085/4885 |
| US-11332464-B2 | Inhibitors of lysine gingipain | ENPEP, PHYKPL, PREP | ALDH1A1 2355/4885TSHR 4691/4885TP53 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.