Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 4/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984199 | 0.92 | MAP3K8 (0.31) | MAP3K8MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL19983721 | 0.90 | HTR2C (0.32) | MEN1MAPTPABPC1KMT2AHTR2C | |
| SCHEMBL19983826 | 0.89 | ABCG2 (0.37) | EPHX2PRMT6KMT2AHTR2CMETAP2 | |
| SCHEMBL19984011 | 0.89 | EGFR (0.34) | MAP3K8MEN1MAPTKMT2AEGFR | |
| SCHEMBL19984241 | 0.87 | RAPGEF4 (0.32) | HTR2C | |
| SCHEMBL19984177 | 0.86 | HTR2C (0.39) | EPHX2PRMT6KMT2AHTR2CMETAP2 | |
| SCHEMBL19984087 | 0.86 | SLC6A2 (0.34) | MAP3K8MAPK13EIF2AK2MAPK12MAPK11 | |
| SCHEMBL19983703 | 0.85 | LCK (0.37) | — | |
| SCHEMBL19983727 | 0.85 | ABL1 (0.36) | MEN1MAPTKMT2AHTR2C | |
| SCHEMBL19984127 | 0.85 | NUDT1 (0.36) | MAP3K8EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |