Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 7/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983848 | 0.89 | MAP3K8 (0.32) | EGFRMAPTKMT2AMEN1MAP3K8 | |
| SCHEMBL19984199 | 0.86 | MAP3K8 (0.31) | EGFRMAPTKMT2AMEN1MAP3K8 | |
| SCHEMBL19983844 | 0.83 | ALDH1A1 (0.35) | NAMPTALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL19983721 | 0.83 | HTR2C (0.32) | NAMPTMAPTKMT2AMEN1 | |
| SCHEMBL19984241 | 0.82 | RAPGEF4 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL19983826 | 0.82 | ABCG2 (0.37) | KDM4EGAAKMT2A | |
| SCHEMBL19984007 | 0.81 | MAT2A (0.34) | SYKNPC1RAB9A | |
| SCHEMBL19984177 | 0.81 | HTR2C (0.39) | ALDH1A1KMT2A | |
| SCHEMBL19984087 | 0.81 | SLC6A2 (0.34) | EGFRMAP3K8 | |
| SCHEMBL16626710 | 0.80 | NAMPT (0.38) | TSHRNAMPTMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |