Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984177 | 0.90 | HTR2C (0.39) | KMT2AALDH1A1HTR2C | |
| SCHEMBL19983826 | 0.89 | ABCG2 (0.37) | KMT2AHTR2CLMNACSNK2A1GAA | |
| SCHEMBL19983733 | 0.88 | SLC6A2 (0.37) | MEN1KMT2AHTR2CMAPTCYP1A2 | |
| SCHEMBL19984087 | 0.88 | SLC6A2 (0.34) | HTR2CSLC6A2SLC6A4 | |
| SCHEMBL19984127 | 0.87 | NUDT1 (0.36) | CYP1A2CYP2C9CYP2C19SLC6A2SLC6A4 | |
| SCHEMBL19983883 | 0.86 | HTR2C (0.32) | HTR2CSLC6A2SLC6A4 | |
| SCHEMBL19983703 | 0.85 | LCK (0.37) | — | |
| SCHEMBL19983740 | 0.85 | CYP11B1 (0.35) | ALDH1A1MAPTLMNAKDM4ESLC6A2 | |
| SCHEMBL19983848 | 0.85 | MAP3K8 (0.32) | MEN1KMT2AHTR2CMAPT | |
| SCHEMBL19983893 | 0.84 | HTR2C (0.32) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |