Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983913 | 0.90 | GPR84 (0.38) | CHRNB2CHRNA7CHRNA4ADORA2AADORA1 | |
| SCHEMBL19984194 | 0.88 | GPR84 (0.39) | CHRNB2CHRNA7CHRNA4PTGS2GPR84 | |
| SCHEMBL19983880 | 0.88 | MEN1 (0.36) | CHRNB2CHRNA7CHRNA4ADORA2AADORA1 | |
| SCHEMBL19984013 | 0.86 | HTR2A (0.35) | CHRNB2CHRNA7CHRNA4ADORA2AHTR2A | |
| SCHEMBL19983854 | 0.85 | APP (0.39) | CHRNB2CHRNA7CHRNA4ADORA1GPR84 | |
| SCHEMBL19983892 | 0.83 | PTGS2 (0.46) | CHRNB2CHRNA7CHRNA4PTGS2GPR84 | |
| SCHEMBL19984005 | 0.81 | HTR2A (0.44) | CHRNB2CHRNA7CHRNA4PTGS2GPR84 | |
| SCHEMBL19983894 | 0.81 | GPR84 (0.39) | CHRNB2CHRNA7CHRNA4GPR84HTR2A | |
| SCHEMBL19983861 | 0.80 | GPR84 (0.41) | CHRNB2CHRNA7CHRNA4PTGS2GPR84 | |
| SCHEMBL19984197 | 0.80 | GPR84 (0.49) | CHRNB2CHRNA7CHRNA4PTGS2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |