Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983867 | 0.88 | HTR2C (0.42) | HTR2AALDH1A1CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983715 | 0.88 | HTR2A (0.42) | HTR2AALDH1A1ALKBH5FTONR3C1 | |
| SCHEMBL19983754 | 0.88 | HTR2A (0.45) | HTR2AALDH1A1ALKBH5FTONR3C1 | |
| SCHEMBL19984197 | 0.88 | GPR84 (0.49) | HTR2ACHRNB2CHRNA7CHRNA4PTGS2 | |
| SCHEMBL19983891 | 0.88 | GPR84 (0.49) | HTR2AALKBH5FTONR3C1CHRNB2 | |
| SCHEMBL19984215 | 0.86 | GAA (0.47) | HTR2AALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL19984167 | 0.86 | NR3C1 (0.42) | NR3C1NR3C2CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL19983847 | 0.86 | TBXAS1 (0.42) | HTR2AALDH1A1NR3C1NR3C2CHRNB2 | |
| SCHEMBL19984000 | 0.85 | HTR2A (0.46) | HTR2AALDH1A1ALKBH5FTONR3C1 | |
| SCHEMBL19983944 | 0.84 | GPR84 (0.40) | HTR2AALDH1A1ALKBH5FTONR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |