Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984005 | 0.88 | HTR2A (0.44) | KDM4EHTR2AALDH1A1NPSR1CHRNB2 | |
| SCHEMBL19984197 | 0.86 | GPR84 (0.49) | HTR2ACYP2D6CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19983891 | 0.86 | GPR84 (0.49) | HTR2CHTR2AHTR1ACHRNB2CHRNA7 | |
| SCHEMBL19983847 | 0.84 | TBXAS1 (0.42) | HTR2AMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL19984167 | 0.84 | NR3C1 (0.42) | MEN1KMT2ALMNACHRNB2CHRNA7 | |
| SCHEMBL19984215 | 0.84 | GAA (0.47) | KDM4EHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL19983944 | 0.82 | GPR84 (0.40) | KDM4EHTR2AALDH1A1HTR1ACHRNB2 | |
| SCHEMBL19983751 | 0.81 | GPR84 (0.40) | KDM4EHTR2AMEN1KMT2AALDH1A1 | |
| SCHEMBL19983900 | 0.80 | CDK2 (0.42) | HTR1AGAAHTR6 | |
| SCHEMBL19983771 | 0.80 | CHRNB2 (0.38) | HTR2CKDM4EHTR2AHTR2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |